CJC 1295 IPA BLEND 10mg

$55.00

FOR RESEARCH SCIENTIFIC STUDIES ONLY- NOT FOR HUMAN/ANIMAL CONSUMPTION/USE

In stock

SKU: CJC-IPA-NO-DAC-1 Categories: ,

Description

 CJC-1295 / Ipamorelin Blend 10Mg

Molecular Formula: C₁₆₅ H₂₇₁ N₄₇ O₄₆ / C₃₈ H₄₉ N₉ O₅
Solubility: Soluble in sterile water; mix gently until fully dissolved.
Research Focus
Synergistic peptide formulation studied for its combined stimulation of the GH axis and pituitary receptor pathways in preclinical research.

Summary

The CJC-1295 / Ipamorelin Blend is a research-use combination of two synthetic peptides designed to study coordinated stimulation of growth hormone pathways. CJC-1295 (no DAC) is a modified GHRH analog that interacts with receptors in the pituitary gland, activating signaling pathways that increase cyclic AMP and promote growth hormone release. Ipamorelin is a selective ghrelin receptor (GHS-R1a) agonist that triggers calcium-dependent signaling, further enhancing the growth hormone response initiated by CJC-1295.

In laboratory studies, this combination is frequently used to examine how the hypothalamus and pituitary work together to regulate growth hormone pulsatility. Research indicates that when the two peptides are administered together, they can produce a stronger and more sustained GH release pattern than either peptide alone. This allows researchers to analyze somatotropic feedback loops, receptor sensitivity, and pulsatile hormone dynamics.

Additional preclinical studies have explored the blend’s effects on cellular energy metabolism, GH binding protein production, and neuroendocrine timing signals. Because each peptide activates a different receptor pathway, using them in combination provides a controlled model for studying cross-communication between GHRH and ghrelin signaling systems.

Mechanism of Action

The CJC-1295 / Ipamorelin Blend combines a GHRH analog (CJC-1295 no DAC) with a selective GHRP analog (Ipamorelin). CJC-1295 stimulates the release of growth hormone by binding to GHRH receptors on pituitary somatotroph cells and activating adenylate cyclase and cAMP pathways. Ipamorelin complements this action by binding to GHS-R1a (ghrelin receptor), initiating intracellular calcium mobilization and further enhancing GH release. Together, these pathways produce additive GH secretion effects that have been used to study pituitary co-activation and growth factor feedback dynamics.